Particle
PARTICLE is a software package for single-particle EM image processing. It provides an integrated computing environment with comprehensive data analysis functions for particle selection, particle classification, 3D
reconstruction and model evaluation. Notable features of the package include a direct method for alignment-free 2D classification, streamlined RCT & tomographic reconstruction and intuitive Visual Scripting for high-throughput image processing.
PARTICLE has been designed for users with all levels of experience in image analysis: while an expert
is able to fine-tune the procedure and parameters for an image-processing
task, a novice can rely on the program itself for a proper setup. Moreover, PARTICLE can be utilized as an
educational platform for users to learn and practice single-particle EM data
processing. A test dataset has been
included in the software distribution for demonstration and exercise.
PARTICLE runs on all
major computer operating systems that include Linux, Mac OS and MS
Windows. The package is developed and
supported by I.A.N.
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